Paris, France

Like all great cities, you can spend months in Paris and barely scratch the surface of the city’s cultural treasures. It has museums galore, stellar shopping and busy cafés perfect for people-watching. Follow Anthony Bourdain’s advice: Do Paris right. Fall in love with Paris.  See signs of the City: Paris.

New York, New York

New York is true to its roots and remains a city of immigrants with inspiring architecture and a thriving arts scene. Take in a show on Broadway, shop in SoHo, spend a lazy day in Central Park and explore the city’s diverse neighborhoods. Inexpensive fun: New York on a budget. See the signs of city: New York. Watch the Lost Girls get lost in NYC.

Rome, Italy

The Eternal City Rome celebrates its long history with monuments, churches and restored ruins that offer a glimpse into life during the days of the great Roman Empire. Celebrate the city’s roots and immerse yourself in the culture over a heaping bowl of pasta and a taste of gelato. See all the reasons why we love the Italians. Hungry? Get a taste of Italy. See Anthony Bourdain’s layover in Rome.

Cancun, Mexico

Miles of beaches, endless luxury accommodations and a nonstop party atmosphere in Cancun have transformed this once sleepy village on the Yucatan coast into one of Mexico‘s most popular tourist attractions, particularly during spring break. Take a tour of Cancun’s best attractions. See the party capital’s life after dark. Looking for a place to dine? Check out Cancun’s must-eat cuisine.

London, England

London is a cosmopolitan city with a unique blend of historic traditions and a hip, modern culture. You can enjoy tea and crumpets and celebrate the city’s royal roots before heading out to a slick gastropub for gourmet dinner and drinks. From the Beatles to the Royals, see why we love the Brits. See the most popular attractions in London. Sport fan? Check out London’s football stadiums.

Miami, Florida

The American Riviera, Hollywood of the East, SoBe, or the Art Deco District — whatever you call it, Miami’s South Beach is hot year-round. The embodiment of excess, South Beach is an international playground offering non-stop nightlife, sandy shores, unique architecture and plenty of eye candy. Spice things up with a stay at Miami’s super-sexy suites. Cool off with a dip in Miami’s best hotel pools. Experience glamour and luxury Miami style.

Orlando, Florida

There’s fun around every corner in Orlando with wild roller coasters, twisting waterslides and theme-park fun. Mickey Mouse certainly plays a starring role in the festivities, but there’s plenty of magic beyond the realm of Disney. Planning a family vacation? Check out these kid-friendly hotels in Orlando. See our list of Orlando’s top 5 attractions. Where do the locals eat? See our picks for best local restaurants.

San Francisco, California

Bring a hearty appetite and good walking shoes to the City by the Bay. For a quintessential San Francisco experience, climb aboard a cable car, peruse the farm-fresh goods at the Ferry Market, stroll through Golden Gate Park and board a ferry to the island of Alcatraz for a dose of history and great city views. Nature lover? See the national parks just outside of San Francisco. Check out the endless things to do in San Francisco.

Myrtle Beach, South Carolina

As the largest resort along South Carolina’s 60-mile Grand Strand, Myrtle Beach is the East Coast’s ultimate vacation hub. The town teems with summertime action along the Strand with beaches, amusement and water parks, restaurants and live entertainment and a host of hotels ready to pamper guests young and old. Taking the whole gang? Check out our picks for family fun in Myrtle Beach.

Branson, Missouri

Branson is an unassuming vacation destination with small-town charm and big-city entertainment in the heart of the Ozark Mountains. Millions of visitors come each year to see a show at any of the 50 theaters and enjoy outdoor fun on the lake. Check out our picks for things to do in Branson.